SpectraGenetics offers full-length cloned human or mouse genes (fosmid-based genomic clones, not cDNA clones) that carry N- or C-terminal GFP, luciferase or epitope tags.

FEATURES:

• Transfection-ready DNA, saving you weeks or months of time
• End-sequence confirmed genomic clones with ~40 kb of genomic sequence per clone
• Select GFP, luciferase or epitope tags
• Select N-terminal or C-terminal location
• Neomycin-resistance in vector backbone for easy production of stable cell lines

APPLICATIONS:
Full-length tagged genomic clones are useful for studies and assay development involving:

• Transcriptional and translational regulation
• Post-translational modification
• Protein subcellular localization
• Protein-protein interactions
• Alternative splicing
• Knockdown of RNA/protein by siRNA/miRNA
• Gene replacement following knockout
• Transgenic production

Courtesy of J. Jarvik, Carnegie Mellon University

Tagged genes in production or in stock are involved in a wide variety of cellular processes and disease states, including:

Apoptosis, cell cycle, mutation and DNA repair, other cancer-related, chromatin remodeling, cytoskeleton, diabetes-related, differentiation, G-proteins and G-protein coupled receptors, interferons and interleukins, small inducible cytokines, other lymphocyte proteins, MAP kinases, NGF-related, and toll-like receptors.

Further information about the tagged genes and a list of our tagged genes in stock or in production can be seen in the Gene Tagging page.

Please contact us to discuss technical details and product availability. Depending on your needs, we may accelerate production of particular tagged genes or add new genes to our product line.